Does LUTHOR HD replace 10X Genomics Data?

No. LUTHOR HD data complements 10x Genomics data. LUTHOR HD will detect more transcripts and genes due to the superior THOR mRNA conversion efficiency. Whereas 10x Genomics v3 typically converts 1 every 3 mRNA molecules into cDNA, THOR captures almost 100% of the mRNA molecules present in each sample. The difference will be primarily noticeable with low expressing genes (which are represented with 1 - 10 transcript copies per cell).